Unlocking The Secrets Of Metabolic Health With DAHLIA4 With Professor Alex Tups

Pushing The Limits

In this conversation, Professor Alex Tups discusses his extensive research on metabolic regulation, focusing on the roles of leptin and insulin in the brain. He shares insights into the discovery of butane, a compound found in the Dahlia flower, and its potential to improve blood sugar regulation and combat neuroinflammation. The discussion highlights the importance of diet, gut health, and the synergistic effects of flavonoids in promoting overall well-being. Professor Tups emphasizes the need for further research and clinical trials to validate the benefits of his findings. In this conversation, Alexander Tups and Lisa Tamati discuss the journey of research from the lab to market, focusing on the supplement Dahlia 4 and its potential impact on health, particularly in relation to metabolic dysregulation and neuroinflammation. They explore the importance of consumer awareness regarding supplements, the role of circadian rhythms in health, and the need for proactive health measures. The discussion emphasizes the unique mechanism of Dahlia 4 in targeting brain inflammation and its implications for conditions like Alzheimer's disease.

Takeaways:

• Leptin and insulin play crucial roles in metabolic regulation.
• Neuroinflammation is a key factor in insulin resistance.
• Dahlia4 is a supplement derived from the Dahlia flower.
• Flavonoids can have synergistic effects on health.
• Diet and gut health significantly impact overall well-being.
• Research shows potential for reversing pre-diabetes.
• Oral hygiene is linked to brain health.
• Clinical trials are ongoing for Dahlia 4's effectiveness.
• The brain is a master organ in regulating metabolism.
• Natural compounds can have varying effects on health. The importance of feedback from users to improve health products.
• Research must translate into real-world applications for maximum impact.
• Basic research is crucial for developing new drugs and supplements.
• Supplements can be brought to market faster than traditional drugs.
• Consumer awareness is key in choosing effective supplements.
• Metabolic dysregulation is a growing concern for aging populations.
• Neuroinflammation may be addressed with targeted supplements.
• Regular eating patterns can support circadian rhythms and metabolic health.
• Dahlia4 targets brain inflammation, offering a unique approach.
• Proactive health measures can mitigate risks of chronic diseases.

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BIO

Alexander Tups pursued his academic journey in Biology, initially studying at the Heinrich Heine University of Duesseldorf and the Philipps University of Marburg. He earned a Diploma in Biology at the latter institution, focusing on Animal Physiology, Genetics, and Developmental Biology. He further advanced his education through a Marie Curie and Boehringer Ingelheim Fonds Scholarship, undertaking a Ph.D. at the Rowett Research Institute, one of the UK's leading nutrition research centres and the Philipps University of Marburg. In 2005 he graduated with "summa cum laude (highest distinction) " for his research on the neuroendocrine mechanism that regulates seasonal body weight. Following his Ph.D., Alexander Tups served as a postdoctoral fellow at the University of Otago from 2006-2008. In recognition of his potential, he received a prestigious junior group leader grant in nutrition research from the German Ministry of Education and Research in 2007, amounting to €1,500,000. This grant allowed him to establish an independent research group called 'neuronal nutrition physiology' at the Philipps University of Marburg, where he explored the impact of nutrient sensing in the brain on the regulation of body weight and glucose homeostasis as one of the youngest independent group leaders in Germany. From 2012-2014 in addition to his group leader role he was Head of Department for Animal Physiology at this institution before he was appointed at the University of Otago in 2014 in Physiology. Throughout his career, Alex Tups has contributed significantly to his field, publishing 48 peer reviewed research papers, the vast majority as lead author. His research has contributed to our understanding of how the brain controls body weight and blood sugar levels. His work has been internationally recognized with notable awards, such as the Michael Harbuz Price in neuroendocrine research in the UK in 2009, the Ernst and Berta Sharrer Award in Germany in 2014, the Commercialisation Researcher Award at Otago University in 2023 and the Research Excellence Price by the Physiological Society of New Zealand in 2023. Alexander reviews research for leading international journals and grant agencies including for Harvard University, the British Welcome Trust and the French and German National Research Agencies. He has advised the city council of his home town, Dunedin, on the impact of artificial lighting on human Health supported by his research which contributed to the installation of modern warm street lighting in Dunedin. His research has been funded by Return on Science, Otago Innovation, the Royal Society of Marsden Fund, the Health Research Council, the German Ministry of Research and the German Research Foundation.

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