Welcome to The Vivo Life Show! Our health, wellness and mindset podcast hosted by founder Josh Bolding.
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Unlock incredible health on the go with Vivo Radio! Tune in to discover our very best health and fitness secrets anytime, any place.
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A podcast about GROWing, one small step at a time. Featuring interviews and recordings about health, tiny house living, fitness, and training for life. Hosted by VTS Coach Mike De Vivo.
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Hi, we are NopeFM. Two friends discuss life and try to change the universe one step per year.
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Learn Spanish con Salsa | Spanish lessons with Latin music and conversational Spanish
Tamara Marie
Learn Spanish free with music-based Spanish lessons and conversations. The best way to learn Spanish and become fluent is through immersion in the culture. Learn to speak Spanish like a native speaker with real-life conversations in Latin American Spanish without boring grammar textbooks. Whether you're a Spanish beginner or intermediate Spanish learner, you'll learn Spanish quickly listening to this podcast. Learning Spanish for adults can be fun, so let us help you go from Spanish beginner ...
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The Blood Podcast summarizes content recently published in Blood, the most cited peer-reviewed publication in the field of hematology.
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TCR-T cells for post-HCT leukemia recurrence; platelets are the predominant source of procoagulant membranes in hemostasis; BR + R maintenance for MCL
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In this week's episode we'll discuss HA-1-targeted T-cell receptor T-cell therapy for recurrent leukemia after hematopoietic stem cell transplantation. Next, we'll learn about how 4D intravital imaging in mice reveals the key role of platelets as a source of procoagulant membranes in hemostasis. Finally, we'll hear about modifications to a common i…
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The 5 Myths Keeping You from Spanish Fluency ♫ 209
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Are the voices in your head holding you back from becoming fluent in Spanish? In this episode, we're uncovering the 5 biggest myths that could be standing in your way. Spoiler: they're all lies! 🙅🏾 Listen to find out: Which of these 5 myths might be stopping you from reaching fluency 🤔 The only 3 real reasons why people struggle to reach fluency 🤐 …
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Outcomes of younger patients with mantle cell lymphoma; M-protein assessment during maintenance therapy in multiple myeloma; in vivo CAR T-cell generation using lentiviral vectors
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In this week's episode we’ll discuss the outcomes of younger patients with mantle cell lymphoma experiencing late relapse; learn more about mass spectrometry-based assessment of M-protein in peripheral blood during maintenance therapy in multiple myeloma and discuss in vivo CAR T-cell generation in non-human primates using lentiviral vectors. Featu…
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Review Series on Factor XI
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Introduced by Associate Editor Dr. Thomas Ortel, this bonus episode discusses the Review Series on Factor XI, published in volume 143 issue 15 of Blood Journal. Dr. Ortel is joined by contributing authors Owen McCarty, PhD, Gili Kenet, MD, and David Gailani, MD. Review Series Articles: Introduction to a review series on factor XI Biology of factor …
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Persistence Pays Off: Cynthia’s Spanish Success Story ♫ 208
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In this episode, Tamara interviews Cynthia, a dedicated member of the Spanish Fluency Club, who shares her journey to becoming fluent in Spanish. She talks about the challenges she’s faced over the years, like dealing with language differences in her Cuban family and the lack of resources when she first started learning. 💬 If you’ve ever felt stuck…
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Protective role of neonatal CMV infection in B-ALL; GVHD targets organoid-forming bile duct stem cells; seven-year outcomes for venetoclax-ibrutinib therapy in MCL
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In this week's episode we'll learn how cytomegalovirus infection early in life depletes preleukemic cells in a mouse model of B-cell acute lymphoblastic leukemia. After that we'll discuss new research, where GVHD targets organoid-forming bile duct stem cells in a TGF-beta-dependent manner. Conversely, a TGF-beta inhibitor protects these stem cells …
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Días lluviosos, conciertos en vivo, y viajes memorables: Una charla con Kesia, Jael, y Kelly (parte 2) ♫ 207
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In this episode, host Tamara Marie continues the conversation with Spanish con Salsa coaches Kesia Sosa, Jael Tórrez, and Kelly Delgado. The discussion covers favorite places to relax in their cities, dream concerts, and the most special trips they’ve taken. This episode is a great opportunity to practice your listening skills as the entire convers…
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Iron, HFE haemochromatosis, and infections; bispecific antibodies improve CAR T-cell response; determinants of outcome in NPM1-mutated AML
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In this week's episode we'll learn about iron, HFE hemochromatosis, and infections. In this large, population-based study, both high and low levels of plasma iron and transferrin saturation were associated with increased risks of infection. Then, we'll discuss how bispecific antibodies improve CAR T-cell response in B-cell malignancies. In-vitro an…
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Platos favoritos, tecnología y supertsiciones: Una charla con Kesia, Jael, y Kelly ♫ 206
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Ready to take your Spanish listening skills to the next level and learn more about Latin American culture? 🎧 In this episode, host Tamara Marie is joined by Language Coaches Jael Tórrez, Kelly Delgado, and Kesia Sosa from the Spanish con Salsa team for an engaging conversation. We talk about cultural superstitions from Nicaragua 🇳🇮, Cuba 🇨🇺, and th…
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Immune fitness and response to taclistamab in R/R multiple myeloma; BCR::ABL1 M244V mutation causes resistance to asciminib; HSCT and myocardial fibrosis in young patients with SCD
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In this week's episode we’ll discuss how immune fitness impacts response to teclistamab in relapsed/refractory multiple myeloma; learn more about a new mechanism of resistance to asciminib conferred by the BCR::ABL1 M244V mutation, and discuss the impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell…
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How to Stay Motivated and Make Consistent Progress with Spanish (Interview with Brittany Davis, Winner of the Spanish con Salsa Members Challenge) ♫ 15 [ENCORE]
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In this episode, we’re talking to a Spanish learner that’s probably a lot like you. Brittany feels a connection with Latino culture, music, and her local community. After downloading numerous apps and stocking up on textbooks, Brittany was still unable to have a conversation in Spanish. 💬 Brittany shares the strategy that led her to a 549-day Spani…
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Decitabine in older patients with AML; EPCR and sickle chronic kidney disease; lymphocyte depletion versus post-transplant cyclophosphamide for mismatched donor transplant for inborn errors of immunity ...
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In this week's episode we’ll discuss the safety and efficacy of decitabine in older patients with AML; learn how heme-induced loss of renovascular endothelial protein C receptor promotes chronic kidney disease in sickle mice, and discuss the outcomes of treatment with HLA-mismatched HSCT with TCRab/CD19 lymphocyte depletion or post-HSCT cyclophosph…
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From Beginner to Conversational Fluency in 90 Days (Interview with Ryan Chindavong) ♫ 85 [ENCORE]
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Do you freeze up when talking to a native Spanish speaker? Is it hard to find someone to speak to in Spanish where you live? If you're struggling to reach conversational fluency in Spanish, or feel nervous about talking to native speakers, this episode is for you. Ryan shares his story about how he went from not knowing what to say during his first…
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Impact of MRD-negative on PFS in myeloma; IPSS-R down-staging before transplant in MDS; hereditary angioedema and venous thromboembolism
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In this week's episode we'll discuss minimal residual disease as an intermediate clinical endpoint for multiple myeloma. Then, we'll learn about IPSS-R downstaging before transplant in MDS. Finally we'll hear about the connection between hereditary angioedema and venous thromboembolism. Featured Articles: EVIDENCE meta-analysis: evaluating minimal …
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Acalabrutinib, venetoclax and obinutuzumab in relapsed/refractory CLL; alternative donor transplantation for severe aplastic anemia; clonal relapse dynamics in AML following allogeneic HCT
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In this week's episode we’ll discuss the safety and efficacy of acalabrutinib, venetoclax and obinutuzumab in relapsed/refractory CLL; learn more about alternative donor transplantation for severe aplastic anemia and discuss clonal relapse dynamics in acute myeloid leukemia following allogeneic hematopoietic cell transplantation. Featured Articles:…
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What is Your Language Learning Type? ♫ 134 [ENCORE]
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What type of language learner are you? The type of language learner you are will influence how quickly you reach Spanish fluency. I will help you improve your Spanish and accelerate your path to fluency by helping you identify your language learning type. 📝 Take the Quiz > https://www.learnspanishconsalsa.com/typequiz Support the Show. ⭐Leave us a …
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Clinical impact of CRh in AML; thrombosis features in a real-life PNH cohort; and restriction of SOX11 expression to EBV-negative Burkitt lymphomas
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In this week's episode we'll learn about the clinical benefit of complete remission with partial hematological recovery, or CRh, in patients with Acute Myeloid Leukemia (AML) treated with molecularly targeted drugs. Then we'll hear about a large cohort of patients with PNH were studied to detail PNH-related thrombotic events, unravel determinants o…
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Learn Nicaraguan Spanish with Music: Amor Fritanguero by La Cuneta Son Machín ♫ 205
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In this episode, Spanish con Salsa Language Coach Jael Tórrez shares the meaning of a song from Nicaragua. 🇳🇮 We’ll break down the lyrics of Amor Fritanguero by La Cuneta Son Machín. 🎶 In this episode, you’ll learn: What is a Nicaraguan fritanga and what makes it unique? 🤷🏾 The meaning of expressions like "abrir la gaza" and "ruge el tigre" 🐯🤔 One …
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Mutational and transcriptional landscape of pediatric BCP lymphoblastic lymphoma; the role of platelet-derived TGF-1 in immune thrombocytopenia; phase 3 trial of mavorixafor in WHIM syndrome
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In this week's episode we’ll discuss the mutational and transcriptional landscape of pediatric BCP lymphoblastic leukemia; learn more about the role of platelet-derived TGF-β1 in immune thrombocytopenia; and discuss the findings from a phase 3 trial of mavorixafor in WHIM syndrome. Featured Articles: Mutational and transcriptional landscape of pedi…
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Learn Puerto Rican Spanish with Music: Hijos del Cañaveral by Residente ♫ 204
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In this episode, we talk about the song Hijos del Cañaveral by Puerto Rican artist Residente. 🎤 I'll break down the lyrics with Spanish con Salsa Language Coach Marla Rivera. Marla is from Puerto Rico and explains how much you can learn about Puerto Rican culture and history from this song. 🎵 In this episode you’ll learn: The Puerto Rican history t…
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GM-CSF coordinates shelter in the cytokine storm; Interleukin-1 as a therapeutic target in TTP; CAR T-cell outcomes across race and ethnicity in LBCL
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In this week's episode we'll discuss new insights on the role of GM-CSF in establishing immune memory. The authors propose that the coordination of opposing immune memory programs, driven by GM-CSF, may be essential to efficient, yet controlled, innate immune responses. After that: Interleukin-1 inhibition in TTP. Researchers explore the potential …
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Review Series on Oncogenic Signaling and Immune Evasion in Hematologic Malignancies
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Introduced by Associate Editor Robert Zeiser, this Review Series focuses on the problem of immune escape by acute myeloid leukemia (AML). The series opens with a review of how AML escapes T-cell–driven elimination and then focuses on how p53 function impinges on AML recognition by immune cells. The series finishes with a summary of new approaches t…
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Marla's Bilingual Story: From Puerto Rico to Pro Interpreter ♫ 203
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In this episode, we get to know Marla Rivera from Puerto Rico, the newest member of our Spanish con Salsa team. Marla talks about how she became a language coach and interpreter, what it was like growing up bilingual in Puerto Rico, and the challenges she faced learning multiple languages. 💬 In this episode you’ll learn: Her experience growing up b…
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Reassessing the CLL prognostic index; ADAMTS13 conformation and risk of relapse in immune-mediated TTP; haploidentical bone marrow transplant in sickle cell disease
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In this week's episode we’ll discuss the prognostic value of the Chronic Lymphocytic Leukemia International Prognostic Index in the era of targeted therapies, learn how peak ADAMTS13 activity can be used to assess ADAMTS13 conformation and risk of relapse in immune-mediated thrombotic thrombocytopenic purpura, and discuss the findings from a phase …
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Puerto Rico vs. República Dominicana: Cultura, Jerga y Diferencias ♫ 202
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In this episode we chat with Sherly from Puerto Rico 🇵🇷 and Kesia from the Dominican Republic 🇩🇴 to uncover the differences and similarities between these two cultures. Learn the fun and unique slang used on each island and pick up tips on understanding and speaking Caribbean Spanish like a local. In this episode you’ll learn: How to say words like…
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A biomarker for disease severity in Wiskott-Aldrich Syndrome; loss of Dnmt3a confers resistance to IFNα; unrelated donor selection in HSCT with PTCy
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In this week's episode we'll discuss assessing risk profile in Wiskott-Aldrich Syndrome, or WAS. Then, we'll learn about how the loss of DNMT3A confers resistance to interferon-alpha in hematopoietic stem cells carrying the JAK2-V617F mutation. Finally, we'll explore unrelated donor selection for AML patients undergoing hematopoietic stem cell tran…
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Cultura puertorriqueña: Una charla con Sherly sobre idiomas, música y tradiciones ♫ 201
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In this episode we meet Sherly from Puerto Rico, a new member of the Spanish con Salsa team, who talks about her challenges and experiences in learning multiple languages. 🌍 Sherly tells us about the Puerto Rican culture such as Christmas traditions, the use of Spanglish in everyday life, and the most popular musical genres: Bomba, Plena, and Regga…
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Nilotinib with or without cytarabine for Philadelphia-positive AML; thrombosis risk in Factor V Leiden and Prothrombin G20210A; ctDNA improves prognostic prediction in relapsed/refractory multiple myeloma ...
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In this week's episode we’ll discuss the safety and efficacy of nilotinib with or without cytarabine in Philadelphia-positive acute lymphoblastic leukemia; learn more about thrombosis risk in double heterozygous carriers of Factor V Leiden and prothrombin G20210A and discuss the utility of circulating cell-free tumor DNA in prognostic prediction in…
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El día perfecto, la fama y las ganas de cantar: Una conversación con el equipo de Spanish con Salsa ♫ 200
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We’re celebrating our 200th episode! 🎉 Join the Spanish con Salsa team for an engaging conversation en español. Whether you're a beginner or an intermediate learner, this is a great chance for you to practice your listening skills with Spanish Language Coaches Jael, Marla, and Yohenia as they discuss different topics. 👂🏽 Listen to the episode to: H…
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Hemophilia prophylaxis with fitusiran vs BPA/CFC; germline NBN variants in pediatric B-ALL; Histone demethylation and cell-intrinsic immune response in AML
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In this week's episode we'll learn about fitusiran prophylaxis in patients with hemophilia A or B, with or without inhibitors. Next we'll hear about new findings that heterozygous germline variants in the NBN gene that are linked to increased risk of B-cell acute lymphoblastic leukemia in children. Finally, we'll explore new insights on the histone…
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Cómo decir “adiós” en Cuba ♫ 199
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In this episode, we learn 14 different ways to say goodbye to someone in Cuba. 🇨🇺 Kelly talks about why Cubans say goodbye in these ways and also how you can ask someone to leave. 👉🏾🚪 In this episode you’ll learn: When and who you should use certain farewell expressions with in Cuba 👋🏾 An expression that you should not repeat outside of Cuba to say…
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Effects of voxelotor on cerebral blood flow in pediatric sickle cell disease; thrombosis in Vexas syndrome; response to tyrosine kinase inhibitors in ABL-class acute lymphoblastic leukemia
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In this week's episode we’ll discuss the effects of voxelotor on cerebral blood flow in pediatric sickle cell disease, learn more about venous and arterial thrombosis in patients with Vexas syndrome, and discuss differential sensitivity to tyrosine kinase inhibitors in ABL-class acute lymphoblastic leukemia. Featured Articles: The influence of voxe…
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Stamping out high-risk myeloma with D-KRd and tandem transplant; plasmin-cleaved VWF in microthrombosis; SCD plasma sensitizes iPSC-derived sensory neurons
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In this week's podcast we'll discuss another step forward in stamping out high-risk myeloma. Then we'll hear about the plasmin-cleaved von Willebrand factor, or VWF, in microthrombosis. Finally we'll hear about new insights into the origins of sickle cell pain. Featured Articles: Daratumumab, carfilzomib, lenalidomide, and dexamethasone with tandem…
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Learn Spanish Numbers with Music [Conteo Regresivo] ♫ 146 [ENCORE]
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Almost everyone knows to count from 1 to 10 in Spanish--before they even learned the language. In this episode, we'll review useful vocabulary related to numbers in Spanish with the salsa song Conteo Regresivo by Gilberto Santa Rosa. Learn how to count from one to 1 million in this episode of the podcast, and some common expressions thaat use Spani…
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Allogeneic transplant in first remission for post-induction molecular MRD; circulating HSPCs actively participate in human hematopoiesis; let-7 miRNAs repress HIC2 to regulate BCL11A transcription and ...
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In this week's episode we’ll discuss the utility of MRD in identifying patients with NPM1 AML who benefit from allogeneic transplant in first remission, learn more about the contribution of circulating hematopoietic stem/progenitor cell subsets to human hematopoietic hemostasis, and discuss the role of Let-7 miRNAs in regulation of BCL11A transcrip…
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Easy Hack to Learn Spanish Past Tense Verbs ♫ 198
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In this episode we focus on grammar, specifically on one of the easiest past tenses in Spanish to remember. 🧠 We learn how simple it can be to start using this tense in conversations, even if it's not always grammatically perfect. 💬 In this episode you’ll learn: The most common use for the imperfect 🔍 How to make sure you’re not using the wrong ver…
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ADAMTS13 recovery in caplacizumab-treated TTP; inhibition of venetoclax-resistant BCL2 variants with sonrotoclax; genomic insights from Castleman disease in twins
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In this week's epside we'll learn about ADAMTS recovery after caplacizumab therapy in patients with immune thrombotic thrombocytopenic purpura. Then, we'll hear about preclinical characterization of sonrotoclax, a potential second-generation BCL2 inhibitor. Finally we'll hear about new insights into the etiology of Castleman disease where researche…
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Learn Cuban Spanish with Music: Guantanamera ♫ 197
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In this episode, Yohenia shows us a very popular song from Cuba due to its great historical significance. 🇨🇺 Let's listen to the lyrics of the song Guantanamera, a Cuban classic of the musical genre Son. 🎶 In this episode you’ll learn: The difference between the musical genres Son and Salsa 💃🏾 Cuban vocabulary: words like Guajira, Guano and Guantan…
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Durable response after tisa-cel in adults with relapsed/refractory follicular lymphoma; high microRNA-145 plasma levels indicate decreased risk of VTE; epigenetic/immunogenetic signature in the prediction ...
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In this week's episode, we’ll discuss the findings from a study assessing responses after treatment with tisagenlecleucel [LM1] in adults with relapsed/refractory follicular lymphoma, learn more about the association between high microRNA-145 plasma levels and decreased risk of future incident venous thromboembolism, and discuss how epigenetic and …
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Language Coaching for Spanish Fluency with Maribel Zapata ♫ 196
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In this episode, we talk about how you can go from a Spanish learner to a Spanish speaker. 🗣💬 We talk with Maribel about the best ways to improve your fluency in Spanish in a fun and effective way. ✅ In this episode you’ll learn: The key to improving your fluency in Spanish 🔑 The mistakes many people make when setting up a learning goal 🚫 The diffe…
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Gut microbiota exploitation by CPX-351 in AML; optimizing anti-myeloma immunity for ASCT; which pediatric ITP patients will develop lupus?
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In this week's episode, we'll discuss gut microbiota exploitation by CPX-351 in acute myeloid leukemia. Then we'll learn about optimizing anti-myeloma immunity. New research shows that regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation. Finally we'll discuss among pediatric patients wi…
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How to Understand Spanish Accents: A Conversation with Maribel Zapata ♫ 195
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In this episode, Maribel shares her experiences traveling through South America and discovering the different existing accents. 🌎 She also tells us what to do when we don't understand what someone says in Spanish. 🤔 In this episode you will learn: The easiest way to start conversations in Spanish 👥💬 The difference between accents from Colombia and …
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Jak2V617F clonal hematopoiesis promotes arterial thrombosis; Staphylococcus aureus infection in Sézary syndrome; clinical features of RAC2-related immunodeficiency
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In this week's episode we’ll discuss the mechanism by which Jak2V617F clonal hematopoiesis promotes arterial thrombosis, discuss how Staphylococcus aureus induces drug resistance in cancer T cells in Sézary syndrome, and learn more about the clinical and functional features of RAC2-related immunodeficiency. Featured Articles: Jak2V617F clonal hemat…
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Learn Cuban Spanish with Music: Cuba Isla Bella by Orishas ♫ 194
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In this episode, Kelly shows us a very energetic song about Cuban identity. 🇨🇺 Cuba Isla Bella by Orishas has different musical genres 🎶 and talks about that even if you are in another country, you will always be Cuban. 🌎 In this episode you’ll learn: Differences between musical genres: Salsa and Timba 🎼 Cuban phrases, like “tírate un paso” 💬 El Ca…
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Molecular mimicry in aplastic anemia; emicizumab prophylaxis in infants with hemophilia; hydroxyurea reduces infections in SCA
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In this week's episode we'll discuss molecular mimicry in aplastic anemia, novel experiments show that antigens associated with viral infections can mimic epitopes presented on hematopoietic progenitor cells. Then, we'll learn about prophylaxis with subcutaneous emicizumab in infants with hemophilia. Finally we'll see how hydroxyurea is associated …
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Creciendo en Cuba: Una Conversación con Kelly Delgado ♫ 193
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In this episode we meet Kelly, a new member of the Spanish con Salsa team, who tells us how she learned English and stories about her country. 🗣🌍 She also tells us about the reality of Cuba and how she managed to move to another English-speaking country, but remains proud of her Cuban nationality. 🇨🇺 In this episode you’ll learn: How to say “swag” …
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Review Series on the Influence of the Tumor Microenvironment on the Pathogenesis of B-Cell Lymphomas
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In this bonus episode of Blood Podcast, Associate Editor, Dr. Freda Stevenson is joined by Drs. Karin Tarte, Andrea Radtke, and Leandro Cerchietti to discuss the Review Series on the influence of the tumor microenvironment on the pathogenesis of B-cell lymphomas. Find the full review series in Blood Journal volume 143 issue 12.…
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Free light chain mass spectrometry in diagnosis and monitoring of AL amyloidosis; T cells of AML patients in remission have distinct RNA signatures; and protective effect of ADAMTS13 in sickle cell mice ...
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In this week's episode we’ll discuss the findings from a study assessing the utility of free light chain mass spectrometry in AL amyloidosis, learn more about distinct single-cell RNA-sequencing signatures of bone marrow T cells of AML patients in remission after an allogeneic stem cell transplant, and discuss why von Willebrand factor clearance is…
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Conversaciones Decembrinas de Colombia ♫ 157 [ENCORE]
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During the fiestas decembrinas (winter holidays), Colombians have a special way of celebrating. In this episode, you'll hear a conversation about making plans with family and all the tasty dishes made in a typical Colombian household. To get access to the transcript from the conversation in this episode, sign up to be a show supporter at learnspani…
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Eculizumab in transplant-associated thrombotic microangiopathy; reclassifying malignant monocytosis; targeting tissue factor in antiphospholipid syndrome
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In this week's episode we'll discuss eculizumab in stem cell transplant-associated thrombotic microangiopathy. Then, we'll learn about reclassifying malignant monocytosis, these newly classified cases have distinct mutational and transcriptional profiles. Finally, we'll hear about targeting the tissue factor coagulation initiation complex prevents …
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