Trust, Teamwork, and Innovation, with Natalie Nairn, Co-founder and CEO of Cyclera Therapeutics

Building Biotechs

This week, I spoke with Natalie Nairn, co-founder and CEO of Cyclera Therapeutics. Natalie is also a Termeer Fellow, and listeners of this podcast know how much I love the Termeer Foundation. We discuss her transition from chemical engineering to biomedical applications. She describes her unexpected path into the fun and volatile startup space, which led to her founding Cyclera. Natalie explains the importance of focusing in biotech development, the promising applications of Cyclera's technology in CNS therapeutics, and the challenges and opportunities in the current funding landscape. She also highlights the value of the Termeer fellowship in her career, the contrast between Boston and Seattle's biotech scenes, and the essential aspects of leadership and team cohesion. Finally, Natalie discusses her future goals for Cyclera and offers valuable advice for aspiring biotech founders.

• Get Natalie's recommended book! The Book of Delights: Essays
• CYpHER: catalytic extracellular targeted protein degradation with high potency and durable effect | Nature Communications
• Connect with Natalie on LinkedIn!
• Learn more about Cyclera Therapeutics

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00:00 Introduction and Early Aspirations

00:33 Journey into Biomedical Engineering

01:19 First Startup Experience

03:40 Founding Cyclera

05:02 Focus on CNS Therapeutics

13:35 Challenges and Strategies in Biotech

15:39 The Termeer Foundation Fellowship

21:26 Biotech Networks: Boston vs. Seattle

26:50 Future of Cyclera and Personalized Medicine

32:45 Conclusion and Final Thoughts