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Identifying The Biomarkers Of Inflammaging - Professor David Furman Interview Series Ep 3

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İçerik Modern Healthspan tarafından sağlanmıştır. Bölümler, grafikler ve podcast açıklamaları dahil tüm podcast içeriği doğrudan Modern Healthspan veya podcast platform ortağı tarafından yüklenir ve sağlanır. Birinin telif hakkıyla korunan çalışmanızı izniniz olmadan kullandığını düşünüyorsanız burada https://tr.player.fm/legal özetlenen süreci takip edebilirsiniz.

In this episode Dr Furman discusses what are the chief components of that make up the iAge clock and how they differ from the markers of acute inflammation. In particular CXCL9 is the main element of the iAge clock while classic marker of inflammation such as CRP, IL-6, TNF-alpha do not appear at all.

Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Furman received his Ph.D. (summa cum laude) from University of Buenos Aires, Argentina, for his work on the identification of factors produced by tumors that enable cancer cells to escape immune attack. During his postdoctoral training at the Stanford School of Medicine, Dr. Furman focused on the application of advanced analytics to study the aging of the immune system in humans and decipher how cumulative inflammatory responses associated with aging lead to an accelerated cardiovascular aging. Dr. Furman has published dozens of scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others.

Dr Furman's paper on iAGE

An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging

https://www.nature.com/articles/s43587-021-00082-y

https://www.biorxiv.org/content/10.1101/840363v1

Prof David Furman’s Lab in Buck Institute Website

https://www.buckinstitute.org/lab/furman-lab/

Stanford 1000 Immunomes Project (KIP) Website:

https://med.stanford.edu/1000immunomes

If you would like to support our channel, we’d love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan

You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan

15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15.

Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/

10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/

$5 off any purchase if users use code MODERN5 at NOVOS Labs https://novoslabs.com/?ref=3957

  continue reading

261 bölüm

Artwork
iconPaylaş
 
Manage episode 343479308 series 2967491
İçerik Modern Healthspan tarafından sağlanmıştır. Bölümler, grafikler ve podcast açıklamaları dahil tüm podcast içeriği doğrudan Modern Healthspan veya podcast platform ortağı tarafından yüklenir ve sağlanır. Birinin telif hakkıyla korunan çalışmanızı izniniz olmadan kullandığını düşünüyorsanız burada https://tr.player.fm/legal özetlenen süreci takip edebilirsiniz.

In this episode Dr Furman discusses what are the chief components of that make up the iAge clock and how they differ from the markers of acute inflammation. In particular CXCL9 is the main element of the iAge clock while classic marker of inflammation such as CRP, IL-6, TNF-alpha do not appear at all.

Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Furman received his Ph.D. (summa cum laude) from University of Buenos Aires, Argentina, for his work on the identification of factors produced by tumors that enable cancer cells to escape immune attack. During his postdoctoral training at the Stanford School of Medicine, Dr. Furman focused on the application of advanced analytics to study the aging of the immune system in humans and decipher how cumulative inflammatory responses associated with aging lead to an accelerated cardiovascular aging. Dr. Furman has published dozens of scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others.

Dr Furman's paper on iAGE

An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging

https://www.nature.com/articles/s43587-021-00082-y

https://www.biorxiv.org/content/10.1101/840363v1

Prof David Furman’s Lab in Buck Institute Website

https://www.buckinstitute.org/lab/furman-lab/

Stanford 1000 Immunomes Project (KIP) Website:

https://med.stanford.edu/1000immunomes

If you would like to support our channel, we’d love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan

You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan

15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15.

Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/

10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/

$5 off any purchase if users use code MODERN5 at NOVOS Labs https://novoslabs.com/?ref=3957

  continue reading

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