December 2021: Association of ECT With Risks of All-Cause Mortality and Suicide in Older Medicare Patients

American Journal of Psychiatry Audio

In this month’s AJP Audio, Dr. Samuel Wilkinson (Yale University, Associate Director of the Yale Depression Research Program) discusses a study looking at the association of electro-convulsive therapy or ECT on all-cause mortality and suicide in Medicare patients with mood and bipolar disorders. Following that, Dr. Ned Kalin, Editor-in-Chief of the Journal discusses the December issue of AJP.

• Wilkinson interview: Effects of ECT on older patients with mood disorders [00:50]
• A brief history of ECT [01:20]
• A troubled history [02:00]
• A backlash against ECT [02:24]
• Improved techniques and practices [03:32]
• Limitations of past research into ECT [04:20]
• Strength of the study [05:33]
• How patients were matched [05:59]
• Limitations of the present study [07:17]
• Treatment of patients going forward [08:18]
• Difficulties in administering and accessing ECT [09:49]
• Next steps in research into ECT and patients with elevated suicide risk [11:14]
• All-cause mortality and ECT [11:57]
• Kalin interview: The December issue of AJP [13:02]
• Major depressive and bipolar disorders [13:13]
• “Neuromodulation Strategies for the Treatment of Depression” [13:42]
• “Association of ECT With Risks of All-Cause Mortality and Suicide in Older Medicare Patients” [14:19]
• “Efficacy and Safety of Lumateperone for Major Depressive Episodes Associated with Bipolar I or Bipolar II Disorder: A Phase 3 Randomized Placebo-Controlled Trial” [15:29]
• Ostacher editorial [17:44]
• “Association Between Systemic Inflammation and Individual Symptoms of Depression: A Pooled Analysis of 15 Population-Based Cohort Studies” [18:18]
• Pariante editorial [20:42]
• “Coordinate-Based Network Mapping of Brain Structure in Major Depressive Disorder in Younger and Older Adults: A Systematic Review and Meta-Analysis” [21:23]
• Putting the issue into context [23:00]

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