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This podcast breaks up BIG health topics, like MTHFR, into small, easy bites. All in ten minutes or less. We'll talk about why folic acid can be toxic, how the MTHFR enzyme is in bed with estrogen, why you want to turn genes off, and how folate and depression are linked. Season 3 features Dr. Kate Naumes, women's health expert, to deep dive into hormones and infertility. Check the show notes at tohealthwiththat.com for more info and downloadable. Have MTHFR? Join genetic rockstars now at com ...
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Doing a good detox protocol takes some preparation and some of the best preparation you can do is finding out if your genes are making detoxification harder for you somewhere. Some gene SNPs have the potential to make detox harder by interfering with phase two conjugation reactions. These include MTHFR, MTR, MTRR, GST, GPX, COMT, HNMT, UGT1A1, SULT…
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Detox is amazing for your body, so why does it feel so awful? The great news is that symptoms of detoxification may be helpful in giving your signals about what is happening. We'll quickly review phases I - III of detoxification, why things can feel bad, where detoxification gets stuck, and how to plan for an easier detoxification.00:00 - Intro00:5…
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In the last episode, we discussed the fact that toxins come from food, air, water, personal care products, and pretty much everything we encounter. Detoxification is an ongoing process that is always at work in your body. Here are the basics about how detoxification happens, what resources your body needs, and why it sometimes feels yucky.Detoxific…
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Toxins are everywhere in modern life, and they have always been a normal part of life because they come from food, bacteria, mold, yeast, air, water, and the soil. Also, now, industrial and agricultural chemicals, the products we use on our skin, teeth, hair, and nails, and things we use to care for our homes like air fresheners, cleaning products,…
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Problems with oxygenation can affect your sleep quality and quantity, leaving you feeling tired, or like you slept but woke up as tired as you were the night before, or just plain exhausted.Iron deficiency and carbon monoxide poisoning are both oxygen problems, not that we think of them that way, but many oxygen problems are more subtle. The classi…
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Sex hormones have a lot to do with how energetic you feel, or how sleepy, or how grumpy. So, let's talk about how estrogen ties into sleep, weight, and metabolism. How progesterone helps insomnia and gets stolen by stress hormones. Also, how testosterone is a feel-good chemical. We'll also talk about xenoestrogens, which come from outside your body…
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There is nothing more frustrating than waking up in the middle of the night and not being able to go back to sleep easily. Nighttime waking is draining and exhausting, and you wake up feeling like you might as well not have bothered with all of those hours of tossing and turning. So, what can you do to help you sleep through the night without wakin…
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Supplements to help you fall asleep are a big topic, and there are many to choose from, but these are my favorite supplements to get you to sleep faster. GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free me…
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MTHFR gene mutations can create a lot of havoc in your life if they aren't properly managed and sleep disorders are just one of the many problems. This video will talk about the most impactful morning and evening sleep routines for MTHFR and also give some tips for the best diet to support great sleep in a person wtih the MTHFR gene mutation.GENETI…
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Sleep anxiety is the horror circle that lies at the intersection of insomnia and anxiety disorders that createes a torturous loop in which a person is worried they won't sleep, and the anxiety ironically prevents them from sleeping. Nightmare.Here's the link to the breaking mental bad habits video: https://youtu.be/5rpKe_hsk3Y?si=8IgE1AlhjsqiPtjx00…
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There are four big categories of sleep disorders and today we'll talk about the last two. Numbers one and two were in the last episode, so if you missed that, check it out here: https://youtu.be/D49k6TlaA_Y?si=It4iWPevrXZnK4d1The third pattern is is hard time falling asleep AND staying asleep and number four is for people who feel like they sleep, …
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There are four big categories of sleep disorders and today we'll talk about the first two. Number one is hard time falling asleep and number two is hard time staying asleep. Taking a look at your sleep pattern can help you to figure out what is actually causing your bad sleep and how you can fix it. We'll talk about the most common causes of each p…
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Sleep is one of our basic bodily functions and a key to good daytime energy and productivity. We'll talk about what sleep is, what it's for, and the basic sleep phases. We will also talk about the role of MTHFR in sleep and also the link between sleep and circadian rhythms. We'll also list eight key ways to maintain a healthy sleep wake cycle for t…
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While we're talking about fatigue, it's important to also talk about what helps you feel energetic, because sometimes knowing what gives you energy can help you understand what is going wrong. We'll talk about sleep, hormones, cellular energy, neurotransmitters and energy, and also rest and energy.00:00 - Intro00:55 - What Is Energy?01:28 - Thyroid…
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Depression and fatigue look incredibly similar, but we treat them totally differently. Maybe it's time for treatment strategies to begin to overlap. We'll talk about how these two conditions intermix, and how you can begin to address both of them. 00:00 - Intro00:35 - Depression and Fatigue are circular01:42 - Depression isn't only neurotransmitter…
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The first step to tackling your fatigue and getting your energy back, is finding out if there is something underneath, causing the fatigue, that you can fix quickly. Some of these simple fixes might need some bloodwork from your doctor, and some will require you to do detective work on your own. The very simple fact is that you can't fix it unless …
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Fatigue and exhaustion are going around - we are all struggling. But why? What is really going on here? What is fatigue, what causes it, and why does everybody I know have it? We'll do a quick overview of the causes of fatigue, including lack of resources, poor sleep, chronic stress, and all the rest. We'll talk about how your body protects itself …
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I have enjoyed this season so much - the interweaving of MTHFR and fertility and the ever-interesting conversation about women's health and hormones. Huge thanks to Dr. Kate Naumes, who made the season so much fun. Without further ado, it is time for the season 4 topic announcement - because this is the #1 symptom that people with MTHFR (and people…
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There is a new fad diet every 20 minutes, or at least it feels that way. It could be paleo, ancestral, keto, the potato diet, the grapefruit diet, the bean diet, and the list goes on. So, how are these fad diets generally, and how are they for fertility? The thing about fad diets is that they work for some people, under some conditions, and for som…
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The best diet for fertility sounds like a big claim to make, but the science is clear about what is needed and what isn't. This episode we'll talk about: What part of the BMI normal range is best for baby-making Basic diet guidelines that are simple to follow Why fruits and vegetables matter so much Why the Mediterranean diet is so effective Why mo…
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Of course there is a perfect way to do things if you have all the money, time, and resources to throw at it, but what about what actually happens in real life? Because let's face it, we're all dealing with medicine IRL. This week we'll talk about: The barriers to good fertility care including insurance or lack of insurance, time, money, location, a…
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This week we're talking about "advanced maternal age" which is the medical term for women having babies over the age of 35. The real problem here comes down to oocyte aging, or aging eggs, which is related to poor ovarian reserve. We'll talk about why egg quality declines with time, what sort of testing your doctor will run, the difference between …
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Iron deficiency anemia can be a significant problem when you're trying to conceive or going into a pregnancy, but even without overt iron deficiency anemia, your iron levels can still have an effect. We'll discuss: Why it's important to test both red blood cell iron levels and also ferritin, the storage form of iron. What iron deficiency anemia fee…
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Overtly low or overtly high thyroid levels are a well known risk factor for infertility, but today we're going to talk about something a little bit less well known, which is subclinical hypothyroid and fertility. Subclinical hypothyroid is when the thyroid tests are on the lower end of normal, but still within normal limits. The patient experiencin…
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MTHFR is involved in so many processes, but it is especially tangled up with fertility for both male and female partners, as well as pregnancy for female partners. This episode we'll talk about: Male factor infertility, sperm count, and sperm morphology 5-LMTHF vs. folic acid use in this situation - what is the standard of care, vs. what might actu…
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The infertility journey can be a difficult path and is often an endurance race with sprints mixed in. This episode is less about mental health expertise, we will defer to therapists, counselors, and mental health professionals for that, and more about starting a conversation around some of the issues we see commonly in our practices. Four of the bi…
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PCOS is one of the more common causes of female-factor infertility because it creates a situation in which ovulation is unpredictable or not occurring and babies can't be made if no good eggs are released. Dr. Kate and Dr. Amy will talk about The diet they typically suggest for PCOS Why a PCOS diagnosis is commonly missed Inositol for PCOS The diff…
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Last week we talked about how endometriosis affects fertility and pregnancy outcomes. This week, let's dive deeper into what is really going on with endometriosis and why it has such far reaching effects for women. We'll discuss Gene SNPs associated with endometriosis The link between inflammation and endo Endometriosis and oxidative stress Treatme…
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Endometriosis is one of the leading causes of female factor infertility and it's responsible for incredibly painful menses, heavy bleeding, and often pain with intercourse as well. This week we'll talk about the links between endometriosis and fertility and next week we'll deep dive into some of the underlying causes, including inflammation and hor…
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Lots of people come to NDs to help them on their fertility journey, but what does an ND actually do? In short, your ND can support your fertility journey in a lot of ways, no matter where you are in the process. We can Balance your hormones and help you with preconception (for both sperm and egg donor) so your baby can have the healthiest start Hel…
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The idea of getting an infertility evaluation is a daunting one, but it gives you such a wealth of valuable information and can help you to steer your treatment in the right direction, for both potential parents, without wasting precious time. Let's talk about: The best doctors to visit for this, and how to get it if you're in an area with limited …
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This week we're talking about a basic tool in every woman's arsenal, it's tracking her period and charting her cycle. Especially on the fertility journey, knowing when you're ovulating and your most fertile window is invaluable, and knowing if you ovulate at roughly the same time every month gives you a great indicator of how things are going in yo…
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Folic acid is the standard of care for both prenatal vitamins and high doses for couples struggling with infertility. So let's look at a compelling research study about using 5-LMTHF as an intervention instead of folic acid for couples who have been struggling with infertility for four years and have already failed high-dose (5000 mcg) folic acid. …
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Seed Cycling sounds too simple to work, but it's a lovely nutritive way to get your menstrual cycle back in balance. This technique uses a combination of four seeds, flax seeds, pumpkin seeds, sesame seeds, and sunflower seeds, to balance and regulate hormones. Seed cycling can help to: Reduce heavy bleeding Reduce cramping Decrease frequency and/o…
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There are so many women's hormone symptoms that women have regularly that we think of as a "normal" part of being a woman, but that might give you some good clues about your fertility. This week we'll expand on this topic from last week and go over symptoms like pelvic pain, cramping, PMS, PMDD, fatigue, chronic acne or hormonal acne, lower abdomin…
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There are lots of red flags in every day life that might indicate a hormone imbalance or other problem that could have fertility consequences. This week we'll talk about the first ones, including: Skipped or missed periods Heavy bleeding or flooding Scanty bleeding (even though it makes for a nicer period) Abnormal hair growth Hair loss Next week, …
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Your annual exam isn't normally the place where you're looking for fertility insights, but if you know where to look there is hidden information in: Your annual bloodwork Your breast exam Your bimanual exam Your pap smear Just because it isn't "about" fertility, doesn't mean this isn't useful. Look here for the show notes with more information abou…
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Last week we talked about basic preconception supplements. This week, we expand on that and add some specifics about: Magnesium Choline Iron and iron infusions Preconception supplements for people with PEMT Preconception supplements for people with COMT Preconception supplements for people with VDR Preconception supplements for people with GST or G…
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Lots of people talk about what you need to take while you're pregnant, but what about the supplements that will boost your fertility and give your baby the healthiest foundation before you conceive? This week we'll discuss: The three preconception must-haves - one of these will definitely surprise you. Supplements for special situations like mother…
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If you're in the ideal situation of planning things out before you decide to get pregnant, then here are the factors you should work on before you try to conceive. What to watch for on your blood work The hormone test that isn't a sex hormone (but is important for healthy pregnancy) The lifestyle habits that might need to change How often you shoul…
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Lots of us have babies without a lot of planning, but if you have the opportunity to plan your family then here is information about: Questions to ask your primary care provider Well woman exam Talking to your dentist What to do with your prescriptions Some hard conversations you might want to have The video version and show notes can be found here…
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Last week, we talked about Estrogen, the primary female sex hormone. This week, let's round out the conversation with a discussion about progesterone, testosterone, the pituitary hormones LH and FSH. We'll talk about: Progesterone and its role in pregnancy Testosterone Signs and symptoms of both testosterone excess and deficiency in men and women T…
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We've all heard of estrogen, of course, but how much do you really know about it? Let's talk about why estradiol is called the Marilyn Monroe hormone. Also, the relative value of hormones vs the absolute value - which matters more? Let's talk about high estrogen symptoms, low estrogen symptoms and some of the causes for both. There is a video versi…
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We already talked about what happens in women's bodies, but what about men? How do men make sperm that will be healthy enough to win the egg race? Let's talk about the four-month process called spermatogenesis. Check the show notes for more about spermatogenesis and MTHFR as well. The complete show notes are here Courses can be found here Genetic R…
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To begin to talk about what is abnormal about women's menstrual cycles, we have to first understand what is normal. Most doctors and experts tend to talk about the two phases of a menstrual cycle, but to more accurately represent the lived experience of having a menstrual cycle, I think four phases are more accurate. These are: Menstrual Follicular…
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It's really tempting to avoid the diagnosis part of fertility - you can just get a bit healthier and it will all work out, right? Except for when it won't. Listen to Dr. Kate Naumes, ND and Dr. Amy Neuzil, ND talk about the biggest reasons why diagnosis is important if you're working on fertility. Here's a hint: The problem might not even be with y…
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For the first episode of this season on infertility, hormones, and how it all ties in with genetics - let's actually talk about what "infertility" means and why you might have passed some major benchmarks without even knowing it. Meet Dr. Kate Naumes, ND our fertility expert and see Dr. Amy Neuzil, ND in the video version. Watch the video version h…
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The internet is full of doomsday prophecies about MTHFR and vaccines, but what does the actual science say? In this episode we'll cover: Dr. Amy's general views of vaccines MTHFR data in the Vaccine Adverse Event Reporting System in the US MTHFR and the smallpox vaccine research A case report about MTHFR and blood clots after the covid-19 vaccine T…
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Living the MTHFR lifestyle means reducing as much toxic exposure as possible and a lot of that comes through skincare. Today, Dr. Amy is talking with Renee Harris, founder of MadeOn skincare. You can find Renee's products at hardlotion.com For the complete show notes, click here. To watch the full, 30 minute interview, click here. To meet other fol…
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Tricia Nelson is an emotional eating expert and the author of Heal Your Hunger: 7 Simple Steps to End Emotional Eating. I am delighted to have the opportunity to talk with her because emotional eating, while it might sound like a departure for me, is a common problem among us MTHFR folks. Anyone with MTHFR, COMT fast, or MAO-A fast can be more susc…
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